In DNA replication, what is the name of the strand that is synthesized discontinuously and is opposite the leading strand?

• A. Antisense strand
• B. Coding strand
• C. Template strand
• D. Lagging strand

Answer: (D)

Verified step by step guidance

1. Understand the process of DNA replication: DNA replication involves the synthesis of new DNA strands from a template strand. This process is semi-conservative, meaning each new DNA molecule consists of one old strand and one new strand.
2. Identify the directionality of DNA strands: DNA strands have directionality, characterized by 5' to 3' and 3' to 5' ends. DNA polymerase can only synthesize new DNA in the 5' to 3' direction.
3. Distinguish between leading and lagging strands: During replication, the leading strand is synthesized continuously in the direction of the replication fork movement, while the lagging strand is synthesized discontinuously.
4. Explain the synthesis of the lagging strand: The lagging strand is synthesized in short segments called Okazaki fragments. These fragments are later joined together by the enzyme DNA ligase.
5. Clarify why the lagging strand is synthesized discontinuously: The lagging strand is synthesized discontinuously because it is oriented in the opposite direction to the movement of the replication fork, necessitating the synthesis of short segments as the fork progresses.