Which of the following statements about the process of DNA replication is false?

• A. The leading strand is synthesized continuously, while the lagging strand is synthesized in Okazaki fragments.
• B. DNA replication is semiconservative, meaning each new DNA molecule consists of one old strand and one new strand.
• C. DNA replication occurs during the G1 phase of the cell cycle.
• D. DNA polymerase can only add nucleotides to the 3' end of a growing DNA strand.

Answer: (C)

Verified step by step guidance

1. Understand the phases of the cell cycle: The cell cycle consists of several phases, including G1, S, G2, and M. DNA replication occurs during the S phase, not the G1 phase.
2. Review the concept of semiconservative replication: In semiconservative replication, each new DNA molecule consists of one old strand and one new strand, which is a true statement.
3. Examine the synthesis of the leading and lagging strands: The leading strand is synthesized continuously, while the lagging strand is synthesized in short segments called Okazaki fragments. This statement is true.
4. Consider the role of DNA polymerase: DNA polymerase can only add nucleotides to the 3' end of a growing DNA strand, which is a true statement.
5. Identify the false statement: Based on the understanding of the cell cycle, the false statement is that DNA replication occurs during the G1 phase. It actually occurs during the S phase.