In DNA replication, what is the characteristic of the 'leading strand' that allows DNA polymerase to synthesize DNA continuously?

• A. It is synthesized in the 3' to 5' direction away from the replication fork.
• B. It requires multiple RNA primers for synthesis.
• C. It is synthesized in the 5' to 3' direction towards the replication fork.
• D. It is synthesized in short fragments called Okazaki fragments.

Answer: (C)

Verified step by step guidance

1. Understand the basic process of DNA replication, which involves the unwinding of the double helix and the synthesis of new DNA strands by DNA polymerase.
2. Recognize that DNA polymerase can only add nucleotides to the 3' end of a growing DNA strand, meaning it synthesizes DNA in the 5' to 3' direction.
3. Identify the 'leading strand' as the strand that is synthesized continuously during DNA replication.
4. Note that the leading strand is synthesized in the same direction as the movement of the replication fork, which is why it can be synthesized continuously.
5. Contrast this with the 'lagging strand', which is synthesized in short fragments called Okazaki fragments, due to its orientation being opposite to the movement of the replication fork.