Which of the following statements about adherens junctions is true?

• A. Adherens junctions connect the actin cytoskeleton of adjacent cells via cadherin proteins.
• B. Adherens junctions are primarily responsible for preventing the passage of molecules between cells.
• C. Adherens junctions are formed by connexin proteins that create channels between cells.
• D. Adherens junctions anchor intermediate filaments to the plasma membrane.

Answer: (A)

Verified step by step guidance

1. Step 1: Begin by understanding what adherens junctions are. Adherens junctions are specialized structures that connect the actin cytoskeleton of adjacent cells, playing a key role in maintaining tissue integrity and facilitating cell-cell adhesion.
2. Step 2: Review the role of cadherin proteins in adherens junctions. Cadherins are transmembrane proteins that mediate cell-cell adhesion by binding to cadherins on neighboring cells and linking to the actin cytoskeleton inside the cell.
3. Step 3: Analyze the incorrect options. For example, adherens junctions do not prevent the passage of molecules between cells; this function is primarily associated with tight junctions. Similarly, adherens junctions are not formed by connexin proteins, which are involved in gap junctions, nor do they anchor intermediate filaments to the plasma membrane, which is a function of desmosomes.
4. Step 4: Compare the correct statement to the function of adherens junctions. The correct statement aligns with the role of adherens junctions in connecting the actin cytoskeleton of adjacent cells via cadherin proteins.
5. Step 5: Conclude by emphasizing the importance of understanding the distinct roles of different cell junctions (e.g., adherens junctions, tight junctions, gap junctions, and desmosomes) in maintaining cellular structure and function.