Which phase of mitosis is the longest?

• A. Metaphase
• B. Anaphase
• C. Telophase
• D. Prophase

Answer: (D)

Verified step by step guidance

1. Understand the stages of mitosis: Mitosis is divided into several phases: prophase, metaphase, anaphase, and telophase. Each phase has distinct characteristics and roles in cell division.
2. Identify the characteristics of prophase: During prophase, the chromatin condenses into visible chromosomes, the nuclear envelope breaks down, and the mitotic spindle begins to form. This phase involves significant cellular reorganization.
3. Compare the duration of each phase: Prophase is generally the longest phase of mitosis because it involves multiple complex processes, such as chromosome condensation and spindle formation, which take more time compared to the other phases.
4. Consider the role of metaphase, anaphase, and telophase: Metaphase involves the alignment of chromosomes at the cell's equatorial plane, anaphase is characterized by the separation of sister chromatids, and telophase involves the reformation of the nuclear envelope and the decondensation of chromosomes.
5. Conclude that prophase is the longest phase: Based on the complexity and the number of events occurring during prophase, it is typically the longest phase of mitosis compared to metaphase, anaphase, and telophase.