A high risk of heart disease correlates with high blood levels of which of the following?

• A. Insulin
• B. Glucose
• C. Low-density lipoprotein (LDL) cholesterol
• D. High-density lipoprotein (HDL) cholesterol

Answer: (C)

Verified step by step guidance

1. Understand the context: Heart disease risk is often associated with certain biomarkers in the blood. These biomarkers can include lipoproteins, glucose, and insulin levels. Lipoproteins are molecules that transport cholesterol and fats in the bloodstream.
2. Differentiate between LDL and HDL cholesterol: Low-density lipoprotein (LDL) cholesterol is often referred to as 'bad cholesterol' because high levels can lead to plaque buildup in arteries, increasing the risk of heart disease. High-density lipoprotein (HDL) cholesterol is known as 'good cholesterol' because it helps remove excess cholesterol from the bloodstream.
3. Correlate LDL cholesterol with heart disease: High levels of LDL cholesterol are strongly correlated with an increased risk of heart disease. This is because LDL contributes to the formation of fatty deposits (plaques) in arteries, which can lead to atherosclerosis and other cardiovascular issues.
4. Understand the role of HDL cholesterol: HDL cholesterol helps transport cholesterol to the liver for excretion, reducing the risk of plaque buildup. Higher levels of HDL cholesterol are generally associated with a lower risk of heart disease.
5. Conclude the correct answer: Among the options provided, the biomarker most strongly correlated with a high risk of heart disease is low-density lipoprotein (LDL) cholesterol.