Which of the following statements about origins of replication is correct?

• A. Origins of replication are specific sequences where DNA replication begins.
• B. Origins of replication are randomly distributed throughout the genome.
• C. Origins of replication are sites where transcription starts.
• D. Origins of replication are only found in prokaryotic cells.

Answer: (A)

Verified step by step guidance

1. Understand that the origin of replication is a specific sequence in the genome where DNA replication begins. This is a key concept in molecular biology.
2. Recognize that origins of replication are not randomly distributed. They are specific sites that are strategically located to ensure efficient replication of the entire genome.
3. Differentiate between replication and transcription. Replication is the process of copying DNA, while transcription is the process of synthesizing RNA from a DNA template. Origins of replication are involved in replication, not transcription.
4. Acknowledge that origins of replication are found in both prokaryotic and eukaryotic cells. In prokaryotes, there is typically a single origin of replication, while eukaryotes have multiple origins to accommodate their larger genomes.
5. Conclude that the correct statement is: 'Origins of replication are specific sequences where DNA replication begins.' This statement accurately describes the function and nature of origins of replication.