What gives keratinocytes their name?

• A. Their ability to produce the protein keratin
• B. Their location in the basal layer of the epidermis
• C. Their role in immune defense within the skin
• D. Their high content of melanin pigment

Answer: (A)

Verified step by step guidance

1. Understand the term 'keratinocytes': These are the primary type of cells found in the epidermis, the outermost layer of the skin. Their name is derived from their ability to produce keratin, a structural protein.
2. Review the function of keratin: Keratin is a tough, fibrous protein that provides strength and protection to the skin, hair, and nails. Keratinocytes synthesize and accumulate keratin as part of their role in maintaining the skin's barrier function.
3. Analyze the options provided: The correct answer should directly relate to the defining characteristic of keratinocytes, which is their ability to produce keratin. Other options, such as their location in the basal layer, immune defense role, or melanin content, do not define their name.
4. Eliminate incorrect options: While keratinocytes are located in the basal layer of the epidermis and play a role in immune defense, these are not the reasons for their name. Similarly, keratinocytes do not have a high content of melanin pigment; that is characteristic of melanocytes.
5. Conclude that the defining feature of keratinocytes is their ability to produce keratin, which is why they are named 'keratinocytes.'