During which phase of mitosis do the chromosomes separate and move to opposite ends of the cell?

• A. Prophase
• B. Anaphase
• C. Metaphase
• D. Telophase

Answer: (B)

Verified step by step guidance

1. Understand the stages of mitosis: Mitosis is divided into several phases: prophase, metaphase, anaphase, and telophase.
2. Identify the key events in each phase: In prophase, chromosomes condense and become visible. In metaphase, chromosomes align at the cell's equatorial plate. In anaphase, sister chromatids separate and move to opposite poles. In telophase, the cell prepares to divide into two.
3. Focus on the phase where chromosomes separate: During anaphase, the sister chromatids are pulled apart by the spindle fibers and move toward opposite ends of the cell.
4. Recognize the role of spindle fibers: Spindle fibers are crucial in anaphase as they attach to the centromeres of the chromatids and help in their movement to opposite poles.
5. Conclude that anaphase is the phase where chromosome separation occurs: Based on the understanding of mitosis phases, anaphase is the correct answer for when chromosomes separate and move to opposite ends of the cell.