Which of the following factors help to increase transcription levels in eukaryotes?

• A. Enhancers
• B. Repressors
• C. Silencers
• D. Insulators

Answer: (A)

Verified step by step guidance

1. Understand the role of enhancers: Enhancers are DNA sequences that can significantly increase the transcription levels of genes. They function by being bound by specific proteins called transcription factors, which help to recruit the transcription machinery to the gene promoter.
2. Learn about repressors: Repressors are proteins that bind to specific DNA sequences and inhibit transcription. They can interfere with the binding of transcription factors or the transcription machinery, thus decreasing transcription levels.
3. Explore silencers: Silencers are DNA sequences that, when bound by specific proteins, can decrease transcription levels. They function similarly to enhancers but in the opposite direction, by recruiting proteins that inhibit transcription.
4. Understand insulators: Insulators are DNA sequences that can block the interaction between enhancers and promoters, thereby preventing the increase in transcription levels. They help maintain the specificity of enhancer-promoter interactions.
5. Identify the correct factor: Among the options provided, enhancers are the factor that helps to increase transcription levels in eukaryotes. They enhance the binding of transcription factors and the transcription machinery to the promoter region, leading to increased gene expression.