Which of the following statements about eukaryotic gene regulation is true?

• A. Eukaryotic genes are regulated only during translation.
• B. Eukaryotic gene expression is primarily regulated at the transcriptional level.
• C. Eukaryotic genes are regulated solely by enhancers.
• D. Eukaryotic gene regulation does not involve epigenetic modifications.

Answer: (B)

Verified step by step guidance

1. Understand that gene regulation in eukaryotes can occur at multiple stages, including transcription, RNA processing, translation, and post-translation.
2. Recognize that transcriptional regulation is a primary control point in eukaryotic gene expression, where transcription factors and other proteins influence the transcription of genes.
3. Consider the role of enhancers, which are DNA sequences that can increase the transcription of associated genes, but note that they are not the sole regulators of gene expression.
4. Acknowledge the importance of epigenetic modifications, such as DNA methylation and histone modification, which can affect gene expression without altering the DNA sequence itself.
5. Evaluate the given statements and identify that the statement 'Eukaryotic gene expression is primarily regulated at the transcriptional level' is true, as it aligns with the understanding of gene regulation in eukaryotes.