Extracellular matrix proteins are produced by ribosomes in which part of a eukaryotic cell?

• A. Golgi Apparatus
• B. Smooth Endoplasmic Reticulum
• C. Rough Endoplasmic Reticulum
• D. Cytosol

Answer: (C)

Verified step by step guidance

1. Understand that the extracellular matrix (ECM) is a network of proteins and carbohydrates that provide structural and biochemical support to surrounding cells.
2. Recognize that proteins destined for secretion or for use in the cell membrane are typically synthesized by ribosomes associated with the endoplasmic reticulum (ER).
3. Differentiate between the rough and smooth endoplasmic reticulum: the rough ER is studded with ribosomes, which are the sites of protein synthesis, while the smooth ER is involved in lipid synthesis and detoxification processes.
4. Identify that the rough endoplasmic reticulum is responsible for the synthesis of proteins that are either secreted from the cell, incorporated into the cell's plasma membrane, or shipped to an organelle.
5. Conclude that since extracellular matrix proteins are secreted from the cell, they are produced by ribosomes on the rough endoplasmic reticulum.