Which stage of mitosis involves sister chromatids separating and moving toward opposite poles?

• A. Metaphase
• B. Prophase
• C. Telophase
• D. Anaphase

Answer: (D)

Verified step by step guidance

1. Understand the process of mitosis, which is the division of a cell's nucleus into two identical nuclei. Mitosis consists of several stages: prophase, metaphase, anaphase, and telophase.
2. Recall the key events of each stage: In prophase, chromosomes condense and spindle fibers begin to form. In metaphase, chromosomes align at the cell's equatorial plane. In anaphase, sister chromatids separate and move toward opposite poles. In telophase, the nuclear envelope reforms around the separated chromosomes.
3. Focus on the question: It asks which stage involves the separation of sister chromatids and their movement toward opposite poles. This is a defining characteristic of anaphase.
4. Visualize the process: During anaphase, the spindle fibers pull the sister chromatids apart, ensuring that each new daughter cell will receive an identical set of chromosomes.
5. Conclude that the correct answer is anaphase, as it is the stage where sister chromatids separate and migrate to opposite poles of the cell.