Multiple Choice
Why do eukaryotic mRNA molecules require a 5' cap and a poly-A tail, whereas prokaryotic mRNA does not?
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15. Gene Expression
Eukaryotic RNA Processing and Splicing
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Which of the following statements about the poly(A) tail of eukaryotic mRNA is true?
A
The poly(A) tail is involved in the splicing of introns.
B
The poly(A) tail is added to the 5' end of the mRNA.
C
The poly(A) tail is composed of guanine nucleotides.
D
The poly(A) tail protects mRNA from degradation.
Verified step by step guidance1
Understand the role of the poly(A) tail in eukaryotic mRNA. The poly(A) tail is a stretch of adenine nucleotides added to the 3' end of the mRNA molecule after transcription.
Recognize the function of the poly(A) tail. It is primarily involved in protecting the mRNA from enzymatic degradation, aiding in the export of the mRNA from the nucleus, and assisting in translation initiation.
Clarify the location of the poly(A) tail. It is added to the 3' end of the mRNA, not the 5' end.
Identify the composition of the poly(A) tail. It is made up of adenine nucleotides, not guanine nucleotides.
Conclude that the correct statement is: 'The poly(A) tail protects mRNA from degradation.' This highlights its protective role against exonucleases that degrade RNA molecules.
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