During which phase of mitosis does a cell transition from metaphase to anaphase?

• A. Prophase
• B. Anaphase
• C. Metaphase
• D. Telophase

Answer: (B)

Verified step by step guidance

1. Understand the sequence of mitosis phases: prophase, metaphase, anaphase, and telophase.
2. Recognize that during metaphase, chromosomes align at the cell's equatorial plane.
3. Identify that the transition from metaphase to anaphase involves the separation of sister chromatids.
4. In anaphase, the sister chromatids are pulled apart toward opposite poles of the cell.
5. Conclude that the transition from metaphase to anaphase is marked by the beginning of chromatid separation.