Which class of globulins makes powerful contributions to both nonspecific resistance and specific immunity?

• A. Delta globulins
• B. Gamma globulins
• C. Alpha globulins
• D. Beta globulins

Answer: (B)

Verified step by step guidance

1. Understand the role of globulins: Globulins are a group of proteins in the blood plasma that play various roles in the immune system and other physiological processes. They are categorized into alpha, beta, gamma, and delta globulins based on their electrophoretic mobility.
2. Focus on gamma globulins: Gamma globulins are a subclass of globulins that primarily consist of immunoglobulins (antibodies). These proteins are crucial for immune responses, as they help identify and neutralize pathogens such as bacteria and viruses.
3. Differentiate nonspecific resistance and specific immunity: Nonspecific resistance refers to general defense mechanisms like inflammation and phagocytosis, while specific immunity involves targeted responses mediated by antibodies and lymphocytes. Gamma globulins contribute to both by acting as antibodies in specific immunity and supporting immune functions in nonspecific resistance.
4. Compare the other globulin classes: Alpha and beta globulins are involved in transport functions (e.g., carrying hormones and lipids) and enzymatic activities, while delta globulins are not typically associated with immune functions. Gamma globulins are unique in their direct role in immunity.
5. Conclude the reasoning: Based on their function as antibodies and their involvement in both nonspecific and specific immune responses, gamma globulins are the class of globulins that make powerful contributions to immunity.