14. DNA Synthesis

The Griffith Experiment

Griffith's Experiment: Bacterial Transformation

Of the way they grew on artificial media.

The "S" bacteria formed smooth appearing colonies.

The "R" bacteria formed rough appearing colonies.

The bacteria that Griffith experimented with were termed "R" and "S" bacteria because:

Genetics - The Transforming Principle - Lesson 12 | Don't Memorise

Griffith's experiment

 consists of sugars, phosphate groups, and bases 

 No. Another group of researchers figured that out. 

 has two strands held together with hydrogen bonds 

 uses three bases to code for one amino acid 

 contains adenine, guanine, thymine, and cytosine 

 was the substance that transformed the bacteria in Griffith's experiment 

Their studies extended Griffith's work.

Avery and his colleagues' 1944 experiment showed that DNA __________.

In his work with pneumonia-causing bacteria and mice, Griffith found that
a. the protein coat from pathogenic cells was able to transform nonpathogenic cells.
b. heat-killed pathogenic cells caused pneumonia.
c. some substance from pathogenic cells was transferred to nonpathogenic cells, making them pathogenic.
d. the polysaccharide coat of bacteria caused pneumonia.

Griffith's Experiment - DNA as Genetic Material II Transformation experiment

 living nonpathogenic; living pathogenic 

 No. It was a pathogenic strain that transformed a nonpathogenic strain. 

 living nonpathogenic; heat-killed pathogenic 

 living pathogenic; heat-killed nonpathogenic 

 heat-killed nonpathogenic; living pathogenic 

 heat-killed pathogenic; living nonpathogenic 

Review the details of Griffith's experiments. Imagine how shocking this discovery was.

During Griffith's experiments with Streptococcus pneumoniae in mice, material from __________ bacteria transformed __________ bacteria.

Episode 003 - Frederick Griffith's Experiment

Griffith experiment | bacterial transformation experiment

Mixing a heat-killed pathogenic strain of bacteria with a living nonpathogenic strain converts the living cells into the pathogenic form.

Mixing heat-killed nonpathogenic bacteria with a living pathogenic strain makes the living strain nonpathogenic.

Infecting mice with nonpathogenic strains of bacteria makes them resistant to pathogenic strains.

Mice infected with a pathogenic strain of bacteria can spread the infection to other mice.

In his transformation experiments, what phenomenon did Griffith observe?

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