Multiple Choice
How do small nuclear RNAs (snRNAs) in the spliceosome initiate the splicing of pre-mRNA?
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15. Gene Expression
Eukaryotic RNA Processing and Splicing
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A mRNA poly-A tail:
A
Prevents translation.
B
Prevents transcription.
C
Marks the RNA for degradation.
D
Protects the mRNA from degradation.
Verified step by step guidance1
Understand the role of the poly-A tail in mRNA. The poly-A tail is a stretch of adenine nucleotides added to the 3' end of eukaryotic mRNA molecules.
Recognize that the poly-A tail is not involved in preventing translation or transcription. Instead, it plays a role in the stability and longevity of the mRNA.
Learn that the poly-A tail helps protect the mRNA from enzymatic degradation in the cytoplasm, thereby extending the mRNA's lifespan.
Consider the process of mRNA degradation. Without the poly-A tail, mRNA molecules are more susceptible to degradation by exonucleases.
Conclude that the primary function of the poly-A tail is to protect the mRNA from degradation, ensuring that it remains intact long enough to be translated into protein.
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