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Animation: Water-Soluble Hormone Pathway

by Pearson
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In this example, epinephrine, a water-soluble hormone, acts as the first messenger. An epinephrine molecule docks with a G protein-coupled receptor, which activates a G protein that activates the enzyme adenylyl cyclase. Adenylyl cyclase converts ATP into cyclic AMP, which quickly diffuses through the cell and acts as a second messenger, triggering further steps in the signaling pathway. In this example, cAMP is shown activating a protein kinase.
In this example, epinephrine, a water-soluble hormone, acts as the first messenger. An epinephrine molecule docks with a G protein-coupled receptor, which activates a G protein that activates the enzyme adenylyl cyclase. Adenylyl cyclase converts ATP into cyclic AMP, which quickly diffuses through the cell and acts as a second messenger, triggering further steps in the signaling pathway. In this example, cAMP is shown activating a protein kinase.