Which of the following organs or tissues can survive the longest without oxygen?

• A. Brain tissue
• B. Skeletal muscle
• C. Liver tissue
• D. Cardiac muscle

Answer: (B)

Verified step by step guidance

1. Understand the role of oxygen in cellular respiration: Oxygen is essential for aerobic respiration, which provides energy (ATP) for cellular functions. Different tissues have varying tolerances to oxygen deprivation based on their metabolic demands and adaptations.
2. Analyze the metabolic activity of each tissue: Brain tissue has a high metabolic rate and relies almost entirely on aerobic respiration, making it highly sensitive to oxygen deprivation. Cardiac muscle also has a high metabolic demand and is less tolerant to oxygen deprivation.
3. Consider the adaptations of skeletal muscle: Skeletal muscle can survive longer without oxygen because it can switch to anaerobic respiration, producing ATP through glycolysis. This adaptation allows it to function temporarily in low-oxygen conditions.
4. Evaluate liver tissue: The liver has a moderate metabolic rate and some capacity for anaerobic metabolism, but it is less adapted to prolonged oxygen deprivation compared to skeletal muscle.
5. Conclude based on the comparison: Skeletal muscle has the greatest ability to survive without oxygen due to its capacity for anaerobic respiration and lower reliance on continuous oxygen supply compared to brain tissue, cardiac muscle, and liver tissue.