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Animation: Adding the 5' Cap and Poly-A Tail

by Pearson
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RNA Processing In eukaryotic cells, the RNA transcript is modified before translation. This step is called RNA processing. The ends of the RNA, a 5 prime untranslated region and a 3 prime untranslated region, do not code for a polypeptide. The actual polypeptide-making instructions begin with the start codon and end just before the stop codon. This portion of the RNA is called the coding segment. RNA processing begins with alteration of the ends of the RNA. A 5 prime cap consisting of a modified guanine nucleotide is added to the 5 prime end. A poly-A tail, made of 30 to 200 adenine nucleotides, is added to the 3 prime end.
RNA Processing In eukaryotic cells, the RNA transcript is modified before translation. This step is called RNA processing. The ends of the RNA, a 5 prime untranslated region and a 3 prime untranslated region, do not code for a polypeptide. The actual polypeptide-making instructions begin with the start codon and end just before the stop codon. This portion of the RNA is called the coding segment. RNA processing begins with alteration of the ends of the RNA. A 5 prime cap consisting of a modified guanine nucleotide is added to the 5 prime end. A poly-A tail, made of 30 to 200 adenine nucleotides, is added to the 3 prime end.