20. Development
Developmental Biology
SPEAKER: So this animation will show us the nuclear transfer we'd seen before, but now we're going to see it as an example where a skin cell nucleus is going to be used to make an embryonic stem cell. So the egg cell has the nucleus removed. The nucleus from a skin cell is then injected into that egg. That egg, you remember, can then initiate development by dividing, making a blastocyst. Here is this important reprogramming phenomena going on, the details of which are still unknown. The cells now begin to divide, continue to divide to make a blastocyst with an inner cell mass. And then, it's from the inner cell mass in that blastocyst that an embryonic stem cell can be derived.
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