For a short time in the 1930s, some physicians prescribed low dos...

Question

For a short time in the 1930s, some physicians prescribed low doses of a compound called dinitrophenol (DNP) to help patients lose weight. This unsafe method was abandoned after some patients died. DNP uncouples the chemiosmotic machinery by making the inner mitochondrial membrane leaky to H+. Explain how this drug could cause profuse sweating, weight loss, and possibly death.

Accepted Answer

everyone. Let's take a look at this question together. Amy osmosis is another pathway of a TP production that utilizes a proton gradient. Since protons cannot freely pass the fossil lipid bi layered membrane proton ions move down their concentration gradient. With the help of hydra filic tunnels called what we have those hydra filic tunnels here and we have our protons that want to pass through this way. And so these protons cannot pass that membrane on their own. So they have to use something called a T. P. Synthesis or answer choice B, which is the correct answer. So we've learned before that 80 P synthesis is a protein And in this case it works similar to a turbine in a hydroelectric power plant. In that here we have our 80p synthesis and we'll draw like a turbine. We have a teepee. And so what it is is this bins like a turbine to allow these protons to flow freely onto the other side down their concentration gradient. So answer choice B. Is the correct answer. And we also know the answer. Choice is incorrect because aqua porn's helped transport water between cells. The potassium channels control the transportation of potassium ions. And lastly sodium channels is incorrect because sodium channels are integral membrane proteins that form ion channels to allow sodium to pass through. So that leaves us with answer choice B. I hope you found this video to be helpful. Thank you and goodbye

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