4. Tissues & Histology

True or False: Connective Tissue Proper is categorized into two types based on their cell types.

A student knows a particular structure is made of connective tissue and they want to know what type of fiber exists in its ground substance. The structure must withstand force from muscles pulling in different directions. What type of fiber is likely used in this connective tissue?

Both collagen fibers & reticular fibers are made of the same protein collagen. How are the two different?

Ehlers-Danlos syndromes are a group of genetic conditions that affect the production of collagen. One symptom of Ehlers-Danlos syndrome can be hyper-elasticity of the skin (skin that stretches much more than normal). This symptom is due to changes in the connective tissue supporting the skin. Relate this symptom to the roles of different fibers in connective tissue:

What is the difference in function between fixed and migratory cells in connective tissue proper?

Fibrocytes are mature fibroblasts. But in some cases, fibrocytes can revert to fibroblasts. Based on their function, when would you expect a fibrocyte may revert to a fibroblast?

Mark the following statements as true or false. If a statement is false, correct it to make a true statement.

a. Fibroblasts store lipids in a large inclusion in their cytoplasm.

Each of the following statements is false. Correct each to make a true statement.

a. Mucous membranes are composed of mesothelium and the underlying loose connective tissue.

Each of the following statements is false. Correct each to make a true statement.

b. Mesothelial cells secrete mucus.

In the disease scleroderma, excessive collagen, glycosaminoglycans, and glycoproteins are produced and deposited in tissues throughout the body. Predict the effects of this disease.

Describe the roles of each of the following components of the ECM:

b. Glycosaminoglycans

Describe the roles of each of the following components of the ECM:

e. Glycoproteins (cell-adhesion molecules)