21. The Immune System

Which of the following is not involved in the activation of a B cell?

a. Antigen

b. Helper T cell

c. Cytokine

d. Cytotoxic T cell

Terrence has severe asthma and allergies, and is placed on a medication that blocks the functioning of IgE. How would this medication alleviate his symptoms?

Ted finds out that he has been exposed to measles. He is concerned that he might have contracted the disease, so he goes to see his physician. The physician takes a blood sample and sends it to a lab for antibody levels and titers. The results show an elevated level and activity of IgM antibodies to rubella (measles) virus but very few IgG antibodies to the virus. Has Ted contracted the disease?

Which of the following is NOT an organ where clonal selection occurs?

More than one choice may apply.

Which of these antibody classes is usually arranged as a pentamer?

a. IgG

b. IgM

c IgA

d. IgD

All of the following are postulates of the clonal selection theory EXCEPT:

Clonal selection:

Define antibody. Using an appropriately labeled diagram, describe the structure of an antibody monomer. Indicate and label variable and constant regions, heavy and light chains.

Match the following antibodies with the correct definition.

____IgD     

____IgM     

____IgG     

____IgA     

____IgE

a. Antibody found in secretions

b. Most common antibody; crosses the placenta

c. Antibody involved in allergies and parasitic infections

d. Pentamer and potent agglutinating agent

e. Antibody bound to the B cell plasma membrane

Which of the following statements is FALSE?

Mark the following statements as true or false. If a statement is false, correct is to make a true statement.

d. Vaccinations are given to induce the production of the inflammatory response.

Name the five classes of immunoglobulins. Which is most likely to be found attached to a B cell membrane? Which is most abundant in plasma? Which is important in allergic responses? Which is the first Ig to be released during the primary response? Which can cross the placental barrier?

How does the formation of an antigen–antibody complex cause the elimination of an antigen?

Name the five antibody classes and describe where each is most likely to be found in the body.