Which of the following hormones stimulates osteoblasts at the epiphyseal plate?

• A. Insulin
• B. Thyroid hormone
• C. Cortisol
• D. Growth hormone

Answer: (D)

Verified step by step guidance

1. Understand the role of osteoblasts: Osteoblasts are cells responsible for bone formation. They are crucial in the growth and development of bones, particularly at the epiphyseal plate, which is the growth area of long bones.
2. Identify the function of the epiphyseal plate: The epiphyseal plate, also known as the growth plate, is where new bone is produced during childhood and adolescence. It is essential for the longitudinal growth of bones.
3. Review the role of growth hormone: Growth hormone (GH) is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration. It plays a significant role in promoting the growth of bones and cartilage.
4. Connect growth hormone to osteoblast activity: Growth hormone stimulates the activity of osteoblasts at the epiphyseal plate, leading to increased bone formation and growth. This is why it is crucial during the growth phases of childhood and adolescence.
5. Differentiate from other hormones: While insulin, thyroid hormone, and cortisol have various roles in metabolism and growth, growth hormone specifically targets the stimulation of osteoblasts at the epiphyseal plate, making it the correct answer in this context.