Pancreatic digestive secretions are regulated primarily by which hormones released from the small intestine?

• A. Insulin and glucagon
• B. Secretin and cholecystokinin (CCK)
• C. Erythropoietin and aldosterone
• D. Gastrin and ghrelin

Answer: (B)

Verified step by step guidance

1. Step 1: Understand the role of pancreatic digestive secretions. The pancreas releases digestive enzymes and bicarbonate to aid in digestion, and these secretions are regulated by hormones released from the small intestine in response to food entering the duodenum.
2. Step 2: Identify the hormones involved in regulating pancreatic secretions. Secretin is released when acidic chyme enters the small intestine, stimulating the pancreas to release bicarbonate-rich fluid to neutralize the acid.
3. Step 3: Recognize the role of cholecystokinin (CCK). CCK is released in response to fats and proteins in the small intestine and stimulates the pancreas to secrete digestive enzymes.
4. Step 4: Differentiate these hormones from others listed. Insulin and glucagon regulate blood glucose levels, erythropoietin regulates red blood cell production, aldosterone regulates sodium balance, and gastrin and ghrelin are involved in stomach functions and appetite regulation, respectively.
5. Step 5: Conclude that secretin and cholecystokinin (CCK) are the primary hormones released from the small intestine that regulate pancreatic digestive secretions.