Textbook Question
More than one choice may apply.
Chemical mediators of inflammation include
a. Interferon
b. Complement
c. Histamine
d. Antibodies
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21. The Immune System
First-Line Defenses: Chemical Barriers
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In the respiratory burst, __________ are released; these have a potent cell-killing ability.
A
neutrophils
B
platelet-derived growth factors
C
free radicals
D
histamines
Verified step by step guidance1
Understand the context of the respiratory burst: It is a rapid release of reactive oxygen species (ROS) from different types of cells, most notably phagocytes like neutrophils, during the process of phagocytosis.
Identify the key players involved in the respiratory burst: Neutrophils are the primary cells that undergo respiratory burst to kill pathogens.
Recognize the substances released during the respiratory burst: The process involves the production of free radicals, which are highly reactive molecules that can damage or kill cells.
Differentiate between the options provided: Neutrophils are the cells involved, not the substances released. Platelet-derived growth factors and histamines are not related to the respiratory burst.
Conclude that free radicals are the correct answer: Free radicals, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals, are the potent cell-killing agents released during the respiratory burst.
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