What triggers the release of erythropoietin (EPO), leading to the production of new red blood cells?

• A. Low oxygen levels in the blood
• B. Increased carbon dioxide levels
• C. High blood pressure
• D. High oxygen levels in the blood

Answer: (A)

Verified step by step guidance

1. Understand the role of erythropoietin (EPO): EPO is a hormone produced primarily by the kidneys. It plays a crucial role in the production of red blood cells (erythropoiesis) by stimulating the bone marrow.
2. Identify the primary trigger for EPO release: The main stimulus for the release of EPO is hypoxia, which is a condition characterized by low oxygen levels in the blood.
3. Consider the physiological response to low oxygen levels: When oxygen levels in the blood decrease, the kidneys detect this change and respond by increasing the production and release of EPO.
4. Evaluate the other options: Increased carbon dioxide levels, high blood pressure, and high oxygen levels do not directly stimulate EPO release. In fact, high oxygen levels would likely decrease EPO production.
5. Conclude the correct trigger: Based on the understanding of EPO's function and the body's response to hypoxia, low oxygen levels in the blood are the correct trigger for the release of erythropoietin.