In renal physiology, glomerular filtration primarily occurs in which portion of the kidney?

• A. Loop of Henle
• B. Collecting duct
• C. Renal corpuscle (glomerulus and Bowman's capsule)
• D. Proximal convoluted tubule

Answer: (C)

Verified step by step guidance

1. Understand that glomerular filtration is the process by which blood plasma is filtered from the glomerular capillaries into the Bowman's capsule, initiating urine formation.
2. Recall the structure of the nephron, which includes the renal corpuscle (composed of the glomerulus and Bowman's capsule), proximal convoluted tubule, loop of Henle, distal convoluted tubule, and collecting duct.
3. Identify that the renal corpuscle is the site where blood is first filtered; the glomerulus acts as a network of capillaries allowing plasma to pass through, while the Bowman's capsule collects the filtrate.
4. Recognize that other parts of the nephron, such as the proximal convoluted tubule, loop of Henle, and collecting duct, are involved in reabsorption and secretion, not the initial filtration.
5. Conclude that glomerular filtration primarily occurs in the renal corpuscle, specifically at the glomerulus and Bowman's capsule.