In renal physiology, the blood filtrate produced by glomerular filtration is initially captured in the lumen of which structure?

• A. Glomerular capillaries
• B. Efferent arteriole
• C. Bowman’s capsule (capsular space)
• D. Proximal convoluted tubule

Answer: (C)

Verified step by step guidance

1. Understand the process of glomerular filtration: blood is filtered through the glomerular capillaries, where plasma and small solutes pass through the filtration membrane.
2. Identify the structure that directly collects the filtrate after it passes through the glomerular capillaries; this is the space surrounding the glomerulus known as Bowman’s capsule (or capsular space).
3. Recognize that the filtrate is initially captured in the lumen of Bowman’s capsule before it moves into the proximal convoluted tubule for further processing.
4. Note that the efferent arteriole carries blood away from the glomerulus but does not collect filtrate; it is part of the blood flow, not the filtrate pathway.
5. Summarize that the correct answer is Bowman’s capsule because it is the first structure to receive the filtrate produced by glomerular filtration.