A cell's hormonal sensitivities are determined by the:
(a) Chemical nature of the hormone
(b) Quantity of circulating hormone
(c) Shape of the hormone molecules
(d) Presence or absence of appropriate receptors
(e) Thickness of its plasma membrane

Verified step by step guidance

1. Understand that a cell's hormonal sensitivity depends on its ability to recognize and respond to specific hormones.
2. Recall that hormones exert their effects by binding to specific receptors either on the cell surface or inside the cell.
3. Recognize that the presence or absence of these appropriate receptors determines whether a hormone can influence the cell.
4. Note that while the chemical nature, quantity, and shape of the hormone are important for hormone function, the cell's sensitivity specifically depends on receptor availability.
5. Conclude that the correct factor determining a cell's hormonal sensitivity is the presence or absence of appropriate receptors.

Key Concepts

Hormone-Receptor Specificity

Cells respond to hormones based on the presence of specific receptors that recognize and bind to particular hormone molecules. This receptor-hormone interaction is crucial because only cells with the appropriate receptors can detect and respond to a given hormone, determining the cell's hormonal sensitivity.

Chemical Nature and Shape of Hormones

Hormones vary chemically (e.g., steroids, peptides) and structurally, which affects how they interact with receptors. The shape and chemical properties of a hormone must complement the receptor's binding site, ensuring a precise fit that triggers the correct cellular response.

Hormone Concentration and Cellular Response

The quantity of circulating hormone influences the strength of the cellular response. Higher hormone levels can increase receptor activation, but sensitivity also depends on receptor availability and affinity, making hormone concentration a key factor in hormonal signaling.