A minimal genetic code requires only 21 codons—one for each amino acid, and one for a stop signal. Given this, what advantage might be offered by having a code with 64 codons?
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1
Understand that the genetic code is composed of codons, which are sequences of three nucleotides.
Recognize that there are 64 possible codons (4 nucleotides: A, U, G, C, each can be in one of three positions, so 4^3 = 64).
Consider that only 21 codons are needed for a minimal genetic code: 20 for amino acids and 1 for a stop signal.
Explore the concept of redundancy or degeneracy in the genetic code, where multiple codons can code for the same amino acid.
Discuss how this redundancy can provide a protective mechanism against mutations, as changes in the third nucleotide of a codon often do not change the amino acid (wobble position).
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Codons and Amino Acids
Codons are sequences of three nucleotides in DNA or RNA that correspond to specific amino acids or stop signals during protein synthesis. The genetic code is composed of 64 possible codons, which allows for the encoding of 20 standard amino acids and additional signals, providing a framework for translating genetic information into functional proteins.
The genetic code exhibits redundancy, meaning that multiple codons can code for the same amino acid. This redundancy can provide a buffer against mutations, as changes in the DNA sequence may not always lead to changes in the protein produced, thereby enhancing the stability and adaptability of organisms.
Having a genetic code with 64 codons allows for greater flexibility and complexity in protein synthesis. This can lead to the evolution of new proteins with novel functions, enabling organisms to adapt to diverse environments and challenges, ultimately contributing to evolutionary success and diversity.