For a short time in the 1930s, some physicians prescribed low doses of a compound called dinitrophenol (DNP) to help patients lose weight. This unsafe method was abandoned after some patients died. DNP uncouples the chemiosmotic machinery by making the inner mitochondrial membrane leaky to H+. Explain how this drug could cause profuse sweating, weight loss, and possibly death.
Play a video:
This video solution was recommended by our tutors as helpful for the problem above.
Was this helpful?
Master Chemiosmosis with a bite sized video explanation from Jason Amores Sumpter