The induced fit model of enzyme catalysis states that _____________.

• A. the enzyme and substrate do not interact until the reaction is complete
• B. the enzyme changes its shape upon substrate binding to better fit the substrate
• C. the substrate is permanently altered to fit the enzyme's active site
• D. the enzyme's active site is a rigid structure that perfectly matches the substrate before binding

Answer: (B)

Verified step by step guidance

1. Understand the concept of the induced fit model: This model explains how enzymes interact with substrates during catalysis. Unlike the lock-and-key model, the induced fit model suggests that the enzyme's active site is flexible and changes shape upon substrate binding.
2. Recognize the key feature of the induced fit model: The enzyme undergoes a conformational change to better accommodate the substrate, enhancing the efficiency of the catalytic process.
3. Eliminate incorrect options: Review the provided choices and discard those that contradict the induced fit model. For example, the idea that the enzyme's active site is rigid or that the substrate is permanently altered does not align with this model.
4. Focus on the correct explanation: The induced fit model emphasizes that the enzyme changes its shape upon substrate binding to create a better fit, facilitating the reaction.
5. Summarize the concept: The induced fit model highlights the dynamic nature of enzyme-substrate interactions, where the enzyme adapts its structure to optimize catalysis.