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Biochemistry
Learn the toughest concepts covered in Biochemistry with step-by-step video tutorials and practice problems by world-class tutors
8. Protein Function
Hemoglobin Binding in Tissues & Lungs
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1
concept
Hemoglobin Binding in Lungs & Tissues
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Hemoglobin Binding in Lungs & Tissues
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3
concept
Hemoglobin Binding in Lungs & Tissues
8m
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4
Problem
In the lungs, the _________ pressure of CO2 causes hemoglobin to _________ CO2 and H+. The _________ pressure of O2 causes O2 to _________ hemoglobin, allowing for its transportation to the tissues.
A
Low; Bind; Low; Release.
B
High; Bind; Low; Release.
C
High; Bind; High; Release.
D
Low; Release; High; Bind.
E
High; Release; Low; Bind.
F
Low; Release; Low; Bind. Blood pH in Tissues ≈ 7.2 Blood pH in Lungs ≈ 7.6 Blood pH ≈ 7.4
5
Problem
Which of the following explains why hemoglobin in RBCs binds to O 2 in the lungs but releases O2 in muscle tissues? (Select all that apply).
A
pH is lower in the lungs than in the tissues.
B
pCO2 is lower in the lungs than in the tissues.
C
BPG is produced at higher levels in tissues compared to the lungs.
D
The temperature of the lungs is generally higher than the temperature in actively contracting muscle tissues.
E
None of the above are true.
6
Problem
How is the vast majority of carbon dioxide transported in the blood from the tissues to the lungs?
A
As diffused gas bubbles of CO2, just as in carbonated soft drinks.
B
As bicarbonate ions (HCO3-).
C
As carbamate groups bound directly to deoxyhemoglobin.
D
As carbon monoxide.
E
As carbon compounds and oxygen radicals.