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Biochemistry
Learn the toughest concepts covered in Biochemistry with step-by-step video tutorials and practice problems by world-class tutors
7. Enzyme Inhibition and Regulation
Phosphorylation
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1
concept
Phosphorylation
2m
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2
concept
Phosphorylation
3m
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3
Problem
During kinase phosphorylation, which phosphate group is removed from ATP in the figure below?
A
α
B
β
C
γ
D
α and β
E
β and γ
4
concept
Phosphorylation
5m
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5
Problem
Covalent modification of an enzyme usually involves phosphorylation / dephosphorylation of:
A
Lysine residue.
B
Proline residue.
C
Serine residue.
D
Aspartate residue.
6
Problem
When the active site of an enzyme is phosphorylated on one of its catalytic amino acid residues, the overall _______________ charge of phosphate groups would _____________ the affinity for a polar, negatively charged substrate.
A
positive; lower.
B
negative; lower.
C
negative; increase.
D
positive; increase.
E
positive; not change.
F
neutral; not change.