in this video, we're going to begin our discussion on the amino acid, one letter codes for all 20 of the standard amino acids. So it turns out that the one letter amino acid codes are just a little bit more challenging to memorize than the three letter amino acid codes. But that just has to do with the fact that their arm or one letter abbreviations of frenetic origin and so recall with our previous lessons on the three letter amino acid codes that there were only four amino acids with frenetic three letter abbreviations. But with our one letter amino acid codes, there are actually eight amino acids with fanatic one letter abbreviations, so that's double the amount. And that's why they're a little bit more challenging to memorize. But if we're able to commit all eight of these one letter abbreviations of phonetic origin toe memory, then memorizing all of the other one letter abbreviations are gonna be super super easy for you guys, and we'll be able to see how that works in our next lesson video. But for now, down below, in this box, we have the 81 letter symbols of frenetic origin, organized in alphabetical order. And so what you'll see is in the first blank for each of these amino acids, we need to think, What letter could we place to fill the sound phonetically and reveal the one letter code and the second blank? And so for Argentine, it's pretty clear that if we put in our into this blank here, we can fill the sound phonetically. And so it's not. It's sound is gonna be Argentine, and it's one letter code will be our now for a spare gene. We have this blank to fill, and so if we put an end into this blank, we can fill the sound phonetically for a spare gene. And it's one letter code is end for a Spartak acid. If we put a D here for a Spartak, it will reveal its one letter code of D Now for glue tam mech acid in the glue tannic part. If we put a E down here, we can fill the sound phonetically to give it a one letter symbol of une and for glutamine up at the top here. If we put a queue in here, it actually fill the sound phonetically, so it'll say cute, I mean and glutamine. Q. Two means sound very similar. And so it's one letter code is cute now for fetal Al Inning. If we put an F in here into this first blank, we can fill the sound phonetically and give it a one letter code of F now for trip to fan. We have to think, How would Bugs Bunny say trip to fan and the way that he would say it is twit, the fan with a W. And so if we were to put a W into this blank, it'll fill the sound phonetically, and it's one letter code is W. And then, of course, last but not least, tyro scenes. One letter code is gonna be why, and we could fill the South phonetically here with the why and so essentially down below. In this image, what we have is a pneumonic to help you guys memorize these eight amino acids with fanatic one letter abbreviations, and that demonic is just nerdy. W Q f or nerdy. Waldo qualifies in fortnight, and so most of you guys know what fortnight is. But for those of you that don't know what it is, fortnight is a competitive video game. And so, uh, most of you guys have either played fortnight. You know, someone that plays fortnight or you know, someone that has played fortnight. But none of you guys know anybody that's played fortnight as much as Waldo. And to tell you the truth, that's why it's so hard to find Waldo in the first place because he spends all of his time playing fortnight up in his room all day and night. And so what? This pneumonic over here? Each letter in the word nerdy represents one of the one letter abbreviations of frenetic origin. And then w Q f, of course, represents, uh, trip to fan glutamine and final outing, which are also one letter abbreviations of phonetic origin. And so you can see here we have this Waldo here and he's pretty nerdy. He's got these glasses on and he's holding up his number one finger and he's got this, uh, sign here, this, uh, name tag that says hello. My name is Waldo, and he's saying, I'm nerdy. I qualified in fortnight, And so, by qualified, what he really means is first place and first place can help us remember that this pneumonic here is for the one letter amino acid codes the first place. And that's why he's holding up number one for the one letter amino acid codes. And so, if you guys can remember nerdy w Q F or nerdy Waldo qualifies in fortnight, then you'll be able to remember you'll be ableto remember the eight amino acids with one letter abbreviations of frenetic origin. And remember, these are the eight abbreviations that you really want to spend most of your time committing to memory. Because once you've committed these eight to memory than memorizing, all of the other amino acids are gonna be much, much easier, and we'll be able to see how that works better in our next lesson video. So I'll see you guys in our next video or will be able to get some practice with these concepts.
2
Problem
Which of the following amino acid 1-letter symbols is of phonetic origin?
A
E.
B
K.
C
T.
D
C.
3
concept
Other Amino Acid 1-Letter Codes
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So in our last lesson video, we talked about the 81 letter amino acid abbreviations of phonetic origin. And remember, it's these eight that you really want to spend most of your time studying and memorizing because those are the hard ones to memorize. And once you've committed those eight to memory that memorizing all of the other one letter abbreviations are gonna be super easy for you guys as we'll see in this video. And so what we've done is we've taken all the other one letter of codes and abbreviations, and we've broken them up into three different groups, and color coded them, as you can see here. So in our first group, we have the Green Group, and what you'll see is that this green color here corresponds with the green color that we see throughout our image and our example down below. Now our next group, what we have is our light blue group. And again this light blue color corresponds with light blue color throughout our image, in our example below. And then our yellow group here corresponds with the yellow amino acid in our image below and so, which will also notices that over here in pink. What we have are the 81 letter amino acid abbreviations of phonetic origin. And we already talked about those in our previous video. So these one letter abbreviations are already provided for us, and so we're not gonna be focusing on these. We're gonna be focusing on the ones that we haven't yet talked about, which are the ones that are in blanks throughout our image. And so in our first group, we have the Green Group. And what you'll see is that for amino acids with unique first letters there, one letter code or symbol is literally just their first letter. And this applies for all of the ones that Aaron Green in our example below. So what you'll see is that Sistine over here has a first letter of C, which is a unique first letter amongst all of the other first letters for all the other amino acids. And because it has a unique first letter, its first letter is going to be It's one letter code and the same applies for histamine. Isil loosen, mutthiah ning searing and veiling all which have unique first letters and their first letters use as their one letter abbreviation so pretty easy, right? So in our next group, what we have is the light blue group and in this group will realizes that some amino acids first letters are not unique. But the first letters are still used for these amino acids, and that's because these amino acids arm or commonly found and proteins throughout nature. And so, for example, both losing and listen start with Letter L. But overall losing is more commonly found in proteins than lacing. And so, for that reason, losing is prioritized with one letter symbol of L. And the same applies for all of the amino acids that are shaded in blue in our example below. And so what you'll see is that Allen in Over here has the first letter of a, which is not a unique first letter. But Allah nine's first letter is still used as it's one letter code, and again that has to do with the fact that Alan in is more commonly found in proteins throughout nature than these other three amino acids that also start with the first letter. A same applies for glazing glistens, first letters, G, and it is not a unique first letter, but it's still used as it's one letter code because it's more commonly found. Loosen we just mentioned up above in our example, which is more common than listening. Pro Lien is more common than female Allan E. And three Inning is more common than trip to fan or tire Issing. And so at this point, what you'll notice is that we've assigned one letter abbreviations for 19 out of the 20 amino acids, and so far, all we've said is that it's just the eight of phonetic origin, and all the other ones are just the first letter so far, so super easy to remember. And so the one amino acid that has not been assigned a code yet is listen, which is this yellow one here, and it's found in this group all by itself. And so, at this point on Lee, a few letters remained in the alphabet that were not already assigned to an amino acid, and so literally, the letter K was chosen for licensing because it's the one that was closest Toe L, which is license first letter that wasn't already taken by another amino acid and so listens one letter abbreviation is literally just the letter K. And so again, when you're trying to memorize these one letter abbreviations instead of trying to memorize all 20 of them, remember that you want to memorize the ones that are in pink. So all the ones that Aaron Pink here are the ones that have one letter abbreviations of phonetic origin, and there are only eight of those. So once you memorize those eight, all you need to know is that listens. One letter code is K, and then all the other ones are just the first letter. So the ones that air in the blue categories and the green categories, there's really no need to try to memorize those because they're literally the first letter of the amino acid itself. So hopefully that will help you guys reduce how much you're trying to memorize. And again, instead of memorizing 20 just focus on memorizing the eight of phonetic origin and then listen is K and that's it. So we'll be able to practice and utilize these memory tools in our practice videos, so I'll see you guys in those videos
4
Problem
Which 1-letter-code is unique in that it is neither the first letter of the amino acid nor phonetic in origin?
A
I.
B
L.
C
K.
D
G.
E
T.
5
Problem
Convert the following amino acids into their 1-letter codes: Glycine, Isoleucine, Valine, Tryptophan, Proline.
A
G, I, V, T, P.
B
L, I, V, Y, P.
C
G, L, V, W, P.
D
G, I, V, W, P.
6
Problem
Complete the amino acid abbreviation chart below from memory.
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7
Problem
Convert the following 3-letter amino acid codes into 1-letter codes to answer the following question:
How does NASA organize a party?
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8
Problem
Convert the following 3-letter amino acid codes into 1-letter codes to reveal the sentence.
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9
Problem
Match the amino acid with the appropriate 1-letter-code.