7. Enzyme Inhibition and Regulation
Binding to the free enzyme.
Binding to the ES-complex.
Blocking the active site.
Altering the active site.
The Vmax of an enzyme-catalyzed reaction will never increase in the presence of an enzyme-inhibitor.
Enzyme inhibitors can be secreted via exocytosis to defend against harmful threats.
At saturating [S], the rate is directly proportional to [enzyme].
The EA for catalyzed & uncatalyzed reactions are equal, but the Keq is more favorable in a catalyzed reaction.
Binding of an inhibitor to an enzyme can be reversible or irreversible.