Biochemistry

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7. Enzyme Inhibition and Regulation

Degree of Inhibition

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Degree of Inhibition

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Degree of Inhibition

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Degree of Inhibition Example 1

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Problem

Calculate the degree of inhibition of an inhibitor on the free enzyme if the [I] = 3 μM and the KI = 6 μM.

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Degree of Inhibition

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Problem

Calculate the degree of inhibition of an inhibitor on the ES-complex if the [I] = 8 μM and the K’I = 0.03 mM.