Biochemistry

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8. Protein Function

Fetal Hemoglobin

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Fetal Hemoglobin

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Problem

Fetal hemoglobin binds oxygen with a ___________ affinity than adult hemoglobin, because it lacks the binding site for ______, which is an allosteric ____________ of oxygen binding to adult hemoglobin.

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Problem

Why is the decreased affinity of fetal hemoglobin for BPG advantageous?