Multiple Choice
In oxidative phosphorylation, which concentration gradient directly provides the energy (proton-motive force) that powers ATP synthase to synthesize ATP?
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Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation
Oxidative Phosphorylation 1
Multiple Choice
In aerobic cellular respiration, which process produces the most ATP per molecule of glucose?
A
Substrate-level phosphorylation in the citric acid (TCA) cycle
B
Pyruvate oxidation (conversion of pyruvate to acetyl-CoA)
C
Oxidative phosphorylation via the electron transport chain and ATP synthase
D
Substrate-level phosphorylation in glycolysis
Verified step by step guidance1
Identify the main stages of aerobic cellular respiration: glycolysis, pyruvate oxidation, the citric acid (TCA) cycle, and oxidative phosphorylation via the electron transport chain and ATP synthase.
Understand that substrate-level phosphorylation occurs directly in glycolysis and the TCA cycle, producing a small, fixed number of ATP molecules per glucose molecule.
Recognize that pyruvate oxidation itself does not produce ATP directly but generates electron carriers (NADH) that feed into the electron transport chain.
Recall that oxidative phosphorylation uses the electrons from NADH and FADH2 to create a proton gradient across the mitochondrial membrane, which drives ATP synthase to produce ATP.
Conclude that oxidative phosphorylation produces the majority of ATP per glucose molecule compared to substrate-level phosphorylation steps, making it the process that yields the most ATP in aerobic respiration.
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