Amine Alkylation Practice Problems
Determine the product produced of the reaction between 3,5-dimethylpyridine and isobutyl iodide.
The antitumor agent triaziquone can cross-link with DNA. Explain why it can form cross-links with DNA.
Suggest a plausible mechanism for the formation of the following quaternary ammonium salt.
Determine the products of the reaction between PhCH2CH2Br and excessive amount of NH3.
Rank the indicated nitrogens within each structure from the least to the most basic.
For the structure shown below, rank the indicated nitrogens from the least to the most basic.
Determine the stronger base in each pair of compounds shown below. Provide a brief explanation for your answer.
(i) CH3CH2CH(OH)NH2 or CH3CH2CH2NH2
(ii) PhNHCH3 or PhCH2NHCH3