Lactones, Lactams and Cyclization Reactions Practice Problems
Consider the following reaction:
Does the following mechanism account for the product's formation?
Give the structures of the products and suggest a plausible mechanism for the reaction shown below.
5-hydroxy-3-methylpentanoic acid forms a cyclic ester (lactone) when it is mixed with a trace amount of acid.
(i) Write the structure of the lactone.
(ii) Suggest a plausible mechanism for its formation.