EAS:Friedel-Crafts Alkylation Mechanism Practice Problems

What is the product formed in the following Friedel-Crafts reaction? (Assume monosubstitution.)

Draw the products formed if benzene undergoes the Friedel-Crafts alkylation with the alkyl chlorides given below.

Propose a mechanism and identify the products formed when benzene undergoes FeBr₃-catalyzed reaction with bromocyclopentane.

Draw the plausible products for the following reactions:

Propose the plausible product(s) and mechanism for the given reaction.

Draw the major product for the reaction of benzene with the given reagents below.

(i) 2-bromo-2-methylbutane, AlCl₃

(ii) 1-chloropropane, AlCl₃

Predict the plausible major product for the reaction of benzene with 2,3-dimethylbutan-1-ol and BF₃.

Naphthalene usually undergoes an electrophilic aromatic substitution at position 1, also referred to as the ⍺ position. What is the major product of the reaction between naphthalene and the specified reagent?

3-methylenepentane and HF

Naphthalene usually undergoes an electrophilic aromatic substitution at position 1, also referred to as the ⍺ position. Determine the major product of the reaction between naphthalene and the reagent listed below:

cyclopentanol and BF₃

Consider the following reaction:

cumene + but-1-ene + HF

i. Provide the reaction showing the generation of the electrophile.

ii. Give the products of the reaction.

Consider the following reaction:

pentan-3-ol + cumene + BF₃

i. Provide the reaction that demonstrates the generation of the electrophile.

ii. Provide the products of the reaction.