Organic Chemistry
The last step in the reaction below is a Diels-Alder reaction. Propose a plausible mechanism for the formation of the dienophile in the reaction.
Regioselectivity is not usually observed in benzyne mechanisms. However, why does the reaction shown produce a highly regioselective product?
Benzyne is a very reactive dienophile due to its unstable triple bond. Predict what product will form when benzyne reacts with 2,3-dimethylenesuccinic acid.
When 1-chloro-2-methylbenzene is treated with sodium amide in ammonia, it undergoes nucleophilic aromatic substitution to form a mixture of two products. Write the products and the mechanism that accounts for the formation of two products.
