Claisen Rearrangement Practice Problems
Allyl groups can be attached to benzene via the initial alkylation of phenol in a Claisen rearrangement. Determine structures A and B in the reaction below. Note: Phenol alkylation is a Williamson ether synthesis.
The following is an example of a Johnson-Claisen reaction, which is a Claisen reaction variant. Provide the possible mechanism for the first step in the reaction.
The following is an example of the Ireland-Claisen reaction, a variation of the Claisen reaction. What is structure B obtained by heating intermediate A?
Eschenmoser-Claisen reaction is a variation of the Claisen reaction. What is the product of the following Eschenmoser-Claisen reaction?