Carboxylation Practice Problems

Write the synthesis of the following molecule using the given starting material and any reagents.

Determine the product of the reaction given below.

Provide a synthetic pathway to prepare the following compound using the given starting material.

Show how the following synthesis can be carried out:

4-bromocyclopent-1-ene → cyclopent-3-ene-1-carboxylic acid

Use any reagents necessary.

Describe how the following synthesis can be carried out:

Use any required reagents and solvents.

Show how the given syntheses can be carried out. Use any necessary reagents.

a. hex-5-en-1-ol → tetrahydro-2H-pyran-2-one

b. ethoxybenzene → 4-ethoxybenzamide

The following transformation can be accomplished using a multistep reaction. Provide a plausible synthetic scheme that includes any required reagents and solvents.

The following transformation can be accomplished through a multistep reaction. Provide a plausible synthetic scheme by incorporating any required reagents and solvents.

The following transformation can be accomplished through a multistep reaction. Show a plausible synthetic scheme by incorporating any additional reagents and solvents:

PhCH(CH₃)CH₂OH → PhCH(CH₃)CH₂COOH

An organic chemist attempts to produce the desired product using the given sequence of reactions, but this product does not form.

(i) Explain why this product does not form.

(ii) Propose a synthesis that would form the desired product.

From the starting material, bromocyclobutane, how could the following compound be synthesized?

Show how the following synthesis can be accomplished using the given starting material and any suitable reagents.

Show how the following synthesis can be carried out using the indicated starting material and any necessary reagents.