7. Substitution Reactions
Nucleophilic Substitution
7. Substitution Reactions Nucleophilic Substitution
9PRACTICE PROBLEM
An intramolecular substitution reaction occurs when (1R,2R)-2-chlorocyclohexan-1-ol is treated with a base like NaOH to produce a cyclic ether. However, when (1S,2R)-2-chlorocyclohexan-1-ol is reacted under the same conditions, a diol forms instead. Explain.
An intramolecular substitution reaction occurs when (1R,2R)-2-chlorocyclohexan-1-ol is treated with a base like NaOH to produce a cyclic ether. However, when (1S,2R)-2-chlorocyclohexan-1-ol is reacted under the same conditions, a diol forms instead. Explain.