Microbiology

Learn the toughest concepts covered in Microbiology with step-by-step video tutorials and practice problems by world-class tutors.

16. Microbial Genetics

DNA Repair Mechanisms

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1

concept

DNA Polymerase Proofreading

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2
Problem

Which of the following reactions is required for proofreading during DNA replication by DNA polymerase?

3
Problem

DNA polymerase proofreading works by removing a mismatched base in the _______ direction, then replaces it with the correct base synthesized in the ________ direction.

4

concept

Mismatch Repair

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5
Problem

Why is methylation important for the mismatch repair mechanism of DNA?

6
Problem

What kind of DNA damage is repaired using the mismatch repair mechanism?

7

concept

Base Excision Repair

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8
Problem

What is the function of DNA glycosylase during base excision repair?

9

concept

Nucleotide Excision Repair

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10
Problem

Which of the following statements about nucleotide excision repair and base excision repair is true?

11

concept

Photoreactivation

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12
Problem

_________ is the enzyme involved in repairing thymine dimers during photoreactivation.

13
Problem

Photoreactivation is able to remove what type of mutation?

14

concept

SOS Repair System

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15
Problem

SOS repair is mediated by a ______________ DNA polymerase:

16
Problem

When the DNA is extensively damaged the cell needs to repair the DNA with the SOS repair mechanism. What is the negative side effect of the cell using SOS repair?